Translations:Calcium channel blocker/27/en

Mechanism of action

A calcium channel embedded in a cell membrane.

In the body's tissues, the concentration of calcium ions (Ca²⁺
) outside cells is normally about 10,000-fold higher than the concentration inside cells. Embedded in the membrane of some cells are calcium channels. When these cells receive a certain signal, the channels open, letting calcium rush into the cell. The resulting increase in intracellular calcium has different effects in different types of cells. Calcium channel blockers prevent or reduce the opening of these channels and thereby reduce these effects.