Translations:Nicotinamide/23/en

Biological role

Nicotinamide occurs as a component of a variety of biological systems, including within the vitamin B family and specifically the vitamin B₃ complex. It is also a critically important part of the structures of NADH and NAD⁺, where the N-substituted aromatic ring in the oxidised NAD⁺ form undergoes reduction with hydride attack to form NADH. The NADPH/NADP⁺ structures have the same ring, and are involved in similar biochemical reactions.