Translations:Vitamin B12/70/en

Malabsorption

Antacid drugs that neutralize stomach acid and drugs that block acid production (such as proton-pump inhibitors) will inhibit absorption of B₁₂ by preventing release from food in the stomach. Other causes of B12 malabsorption include intrinsic factor deficiency, pernicious anemia, bariatric surgery pancreatic insufficiency, obstructive jaundice, tropical sprue and celiac disease, and radiation enteritis of the distal ileum. Age can be a factor. Elderly people are often achlorhydric due to reduced stomach parietal cell function, and thus have an increased risk of B₁₂ deficiency.