Translations:Lipid-lowering agent/7/en
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Research
Investigational classes of hypolipidemic agents:
- CETP inhibitors (cholesteryl ester transfer protein), 1 candidate is in trials. (Anacetrapib) It is expected that these drugs will mainly increase HDL while lowering LDL
- Squalene synthase inhibitor
- ApoA-1 Milano
- Succinobucol (AGI-1067), a novel antioxidant, failed a phase-III trial.
- Apoprotein-B inhibitor mipomersen (approved by the FDA in 2013 homozygous familial hypercholesterolemia.).
- Bempedoic acid, an ATP citrate lyase inhibitor