Translations:Collagen/13/en

Throughout the four phases of wound healing, collagen performs the following functions:

• Guiding function: Collagen fibers serve to guide fibroblasts. Fibroblasts migrate along a connective tissue matrix.
• Chemotactic properties: The large surface area available on collagen fibers can attract fibrogenic cells which help in healing.
• Nucleation: Collagen, in the presence of certain neutral salt molecules, can act as a nucleating agent causing formation of fibrillar structures.
• Hemostatic properties: Blood platelets interact with the collagen to make a hemostatic plug.