Translations:Diabetes medication/53/en

Comparison of anti-diabetic medication
Drug class	Mechanism of action	Advantages	Disadvantages
Sulfonylureas (glyburide, glimepiride, glipizide)	Stimulating insulin release by pancreatic beta cells by inhibiting the KATP channel	Inexpensive Fast onset of action No effect on blood pressure No detrimental effect on low-density lipoprotein Lower risk of gastrointestinal side effects than metformin Convenient dosing	Cause an average of 2–5 kg weight gain Increase the risk of hypoglycemia Glyburide increases risk of hypoglycemia slightly more compared to glimepiride and glipizide