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Found 2 translations.
| Name | Current message text |
|---|---|
| h English (en) | == Excess == {{further|hypervitaminosis D}} Vitamin D toxicity is rare. It is caused by supplementing with high doses of vitamin D rather than sunlight. The threshold for vitamin D toxicity has not been established; however, according to some research, the tolerable upper intake level (UL) is 4,000 [[International unit|IU]]/day for ages 9–71 (100{{nbsp}}μg/day), while other research concludes that, in healthy adults, sustained intake of more than 50,000{{nbsp}}IU/day (1250{{nbsp}}μg) can produce overt [[toxicity]] after several months and can increase serum 25-hydroxyvitamin D levels to 150{{nbsp}}ng/mL and greater. Those with certain medical conditions, such as primary [[hyperparathyroidism]], are far more sensitive to vitamin D and develop [[hypercalcemia]] in response to any increase in vitamin D nutrition, while maternal hypercalcemia during pregnancy may increase fetal sensitivity to effects of vitamin D and lead to a syndrome of intellectual disability and facial deformities. |
| h Japanese (ja) | == 過剰 == {{Anchor|Excess}} {{further/ja|hypervitaminosis D/ja}} ビタミンD中毒はまれである。日光ではなく、高用量のビタミンDを補給することによって引き起こされる。ビタミンD毒性の閾値は確立されていない； しかし、いくつかの研究によると、耐容上限摂取量（UL）は9～71歳で4,000[[:en:International unit|IU]]/日（100{{nbsp}}μg/日）である、 50,000{{nbsp}}IU/日（1250{{nbsp}}μg）以上の持続的摂取は、数ヵ月後に明らかな[[toxicity/ja|毒性]]を生じ、血清25-ヒドロキシビタミンD濃度を150{{nbsp}}ng/mL以上まで上昇させる可能性がある。原発性[[hyperparathyroidism/ja|副甲状腺機能亢進症]]などの特定の病状のある人はビタミンDに対してはるかに感受性が高く、ビタミンD栄養の増加に反応して[[hypercalcemia/ja|高カルシウム血症]]を発症する。妊娠中の母親の高カルシウム血症はビタミンDの影響に対する胎児の感受性を高め、知的障害や顔面奇形の症候群を引き起こす可能性がある。 |