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Found 2 translations.
| Name | Current message text |
|---|---|
| h English (en) | ===Diagnosis=== The assessment of vitamin B<sub>6</sub> status is essential, as the clinical signs and symptoms in less severe cases are not specific. The three biochemical tests most widely used are plasma PLP concentrations, the activation coefficient for the erythrocyte enzyme aspartate aminotransferase, and the urinary excretion of vitamin B<sub>6</sub> degradation products, specifically urinary PA. Of these, plasma PLP is probably the best single measure, because it reflects tissue stores. Plasma PLP of less than 10 nmol/L is indicative of vitamin B<sub>6</sub> deficiency. A PLP concentration greater than 20 nmol/L has been chosen as a level of adequacy for establishing Estimated Average Requirements and Recommended Daily Allowances in the USA. Urinary PA is also an indicator of vitamin B<sub>6</sub> deficiency; levels of less than 3.0 mmol/day is suggestive of vitamin B<sub>6</sub> deficiency. Other methods of measurement, including [[Ultraviolet–visible spectroscopy|UV spectrometric]], [[Fluorescence spectroscopy|spectrofluorimetric]], [[Mass spectrometry|mass spectrometric]], [[thin-layer chromatography|thin-layer]] and [[High-performance liquid chromatography|high-performance liquid chromatographic]], [[Electrophoresis|electrophoretic]], [[electrochemistry|electrochemical]], and enzymatic, have been developed. |
| h Japanese (ja) | ===診断=== ビタミンB<sub>6</sub>の状態を評価することは、重症でない場合の臨床症状や徴候が特異的でないため、不可欠である。最も広く用いられている生化学的検査は、血漿中PLP濃度、赤血球酵素アスパラギン酸アミノトランスフェラーゼの活性化係数、ビタミンB<sub>6</sub>分解産物の尿中排泄量、特に尿中PAの3つである。このうち、血漿PLPは組織の貯蔵量を反映するため、単一の指標としてはおそらく最良のものであろう。血漿PLPが10 nmol/L未満であれば、ビタミンB<sub>6</sub>欠乏を示す。PLP濃度が20 nmol/Lを超えると、米国では推定平均所要量と推奨一日摂取量を設定する際の適正値として選ばれている。尿中PA濃度もビタミンB<sub>6</sub>欠乏の指標であり、3.0 mmol/日未満はビタミンB<sub>6</sub>欠乏を示唆する。その他の測定方法としては、[[Ultraviolet–visible spectroscop/ja|紫外可視分光法]]、[[Fluorescence spectroscopy/ja|分光蛍光分析]]、[[Mass spectrometry/ja|質量分析法]]、[[thin-layer chromatography/ja||薄層]]や[[High-performance liquid chromatography/ja|高速液体クロマトグラフィー]]、[[Electrophoresis/ja|電気泳動]]、[[electrochemistry/ja|電気化学]]、酵素などが開発されている。 |