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Found 2 translations.
| Name | Current message text |
|---|---|
| h English (en) | Niacin [[Enzyme inhibitor|inhibits]] [[cytochrome P450]] enzymes [[CYP2E1]], [[CYP2D6]] and [[CYP3A4]]. Niacin produces a rise in serum [[Bilirubin#Indirect (unconjugated)|unconjugated bilirubin]] in normal individuals and in those with [[Gilbert's Syndrome]]. However, in the Gilbert's Syndrome, the rise in bilirubin is higher and clearance is delayed longer than in normal people. One test used to aid in diagnosing Gilbert's Syndrome involves intravenous administration of nicotinic acid (niacin) in a dose of 50 mg over a period of 30 seconds. {{See also|Niacin#Liver_damage}} |
| h Japanese (ja) | ナイアシン[[Enzyme inhibitor/ja|阻害]][[cytochrome P450|シトクロムP450]]酵素[[CYP2E1/ja|CYP2E1]]、[[CYP2D6/ja|CYP2D6]]および[[CYP3A4/ja|CYP3A4]]を阻害する。ナイアシンは、正常者および[[Gilbert's Syndrome/ja|ジルベール症候群]]の患者において、血清[[Bilirubin#Indirect (unconjugated)|非抱合ビリルビン]]の上昇をもたらす。しかし、ジルベール症候群では、ビリルビンの上昇が正常人より高く、クリアランスが遅れる。ギルバート症候群の診断に用いられる検査のひとつに、ニコチン酸（ナイアシン）を30秒かけて50mg静脈内投与するものがある。 {{See also/ja|Niacin/ja#Liver_damage}} |