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NameCurrent message text
 h English (en)Several [[regulatory sequence]]s in the [[Promoter (biology)|promoter]] region of the human insulin gene bind to [[transcription factor]]s.  In general, the [[A-box]]es bind to [[Pdx1]] factors, [[E-box]]es bind to [[NeuroD]], C-boxes bind to [[MafA]], and [[cAMP response element]]s to [[CREB]]. There are also [[silencer (genetics)|silencers]] that inhibit transcription.
 h Japanese (ja)ヒトインスリン遺伝子の[[Promoter (biology)/ja|プロモーター]]領域にあるいくつかの[[regulatory sequence/ja|制御配列]]は[[transcription factor/ja|転写因子]]に結合する。 一般的に、[[A-box/ja|A-box]]は[[Pdx1/ja|Pdx1]]因子に、[[E-box/ja|E-box]]は[[NeuroD/ja|NeuroD]]に、C-boxは[[MafA/ja|MafA]]に、[[cAMP response element/ja|cAMP応答エレメント]]は[[CREB/ja|CREB]]に結合する。転写を阻害する[[silencer (genetics)/ja|サイレンサー]]も存在する。