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 h English (en)After hypoglycemia has been prolonged, [[cortisol]] and [[growth hormone]] are released to continue [[gluconeogenesis]] and [[glycogenolysis]], while also preventing the use of glucose by other organs. The effects of cortisol and growth hormone are far less effective than epinephrine. In a state of hypoglycemia, the brain also signals a sense of hunger and drives the person to eat, in an attempt to increase glucose.