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 h English (en)Once blood glucose levels fall out of the normal range, additional protective mechanisms work to prevent hypoglycemia. The [[pancreas]] is signaled to release [[glucagon]], a [[hormone]] that increases glucose production by the liver and kidneys, and increases muscle and fat breakdown to supply [[gluconeogenesis]]. If increased glucagon does not raise blood sugar levels to normal, the adrenal glands release [[Adrenaline|epinephrine]]. [[Adrenaline|Epinephrine]] works to also increase [[gluconeogenesis]] and [[glycogenolysis]], while also decreasing the use of glucose by organs, protecting the brain's glucose supply.