All translations
Jump to navigation
Jump to search
Enter a message name below to show all available translations.
Found 2 translations.
| Name | Current message text |
|---|---|
| h English (en) | ===Injectable hydroxocobalamin=== Injection of hydroxocobalamin is used to rectify the following causes of vitamin B<sub>12</sub> deficiency (list taken from the drug prescription label published by the [[Food and Drug Administration (United States)|U.S. Food and Drug Administration]]) * Dietary deficiency of vitamin B<sub>12</sub> occurring in strict vegetarians and in their [[breastfed]] infants (isolated vitamin B<sub>12</sub> deficiency is very rare) * Malabsorption of vitamin B<sub>12</sub> resulting from damage to the stomach, where [[intrinsic factor]] is secreted, or damage to the [[ileum]], where intrinsic factor facilitates vitamin B<sub>12</sub> absorption. These conditions include [[tropical sprue]] and [[nontropical sprue]] (celiac disease). * Inadequate secretion of intrinsic factor, resulting from lesions that destroy the [[gastric mucosa]] (which can be caused by ingestion of corrosives, extensive [[tumors]], and conditions associated with gastric atrophy, such as [[multiple sclerosis]], certain [[endocrine disorders]], [[Iron deficiency (medicine)|iron deficiency]], and subtotal [[gastrectomy]]) * Structural lesions leading to vitamin B<sub>12</sub> deficiency, including regional [[ileitis]], ileal reactions, and malignancies * Competition for vitamin B<sub>12</sub> by [[intestinal parasites]] or bacteria. The [[tapeworm]] from undercooked fish (''[[Diphyllobothrium latum]]'') absorbs huge quantities of vitamin B<sub>12</sub>, and infested patients often have associated gastric atrophy. The [[blind loop syndrome]] may produce deficiency of vitamin B<sub>12</sub> or [[folate]]. * Inadequate use of vitamin B<sub>12</sub>, which may occur if [[antimetabolites]] for the vitamin are employed in the treatment of [[neoplasia]] [[Pernicious anemia]] is the most common cause of vitamin B<sub>12</sub> deficiency. While it technically refers to anemia caused specifically by autoimmune deficiency of intrinsic factor, it is commonly used to refer to B<sub>12</sub>-deficient anemia as a whole, regardless of cause. |
| h Japanese (ja) | ===ヒドロキソコバラミン注射剤=== ヒドロキソコバラミン注射剤は、ビタミンB<sub>12</sub>欠乏の以下の原因を改善するために使用される（リストは[[Food and Drug Administration (United States)/ja|U.S.Food and Drug Administration]]発行の薬物処方ラベルから引用）。 * 厳格な菜食主義者やその[[breastfed/ja|母乳で育てられた]]乳児に起こるビタミンB<sub>12</sub>の食事性欠乏（単独のビタミンB<sub>12</sub>欠乏は非常にまれである） * [[intrinsic factor/ja|内在性因子]]が分泌される胃の損傷、または内在性因子がビタミンB<sub>12</sub>の吸収を促進する[[ileum/ja|回腸]]の損傷に起因するビタミンB<sub>12</sub>の吸収不良。これらの病態には[[tropical sprue/ja|熱帯性スプルー]]や[[nontropical sprue/ja|非熱帯性スプルー]]（セリアック病）が含まれる。 * [[gastric mucosa/ja|胃粘膜]]を破壊する病変（腐食性物質の摂取、広範な[[tumors/ja|腫瘍]]、胃萎縮に関連する病態、例えば[[multiple sclerosis/ja|多発性硬化症]]、ある種の[[endocrine disorders/ja|内分泌疾患]]、[[Iron deficiency (medicine)/ja|鉄欠乏症]]、[[gastrectomy/ja|胃亜全摘術]]など）に起因する内因性因子の分泌不全。 * 局所[[ileitis/ja|回腸炎]]、回腸反応、悪性腫瘍など、ビタミンB<sub>12</sub>欠乏につながる構造的病変がある。 * [[intestinal parasites/ja|腸内寄生虫]]や細菌によるビタミンB<sub>12</sub>の競合。加熱不十分な魚に寄生する[[tapeworm/ja|サナダ虫]]（''[[Diphyllobothrium latum/ja|Diphyllobothrium latum]]''）は大量のビタミンB<sub>12</sub>を吸収し、寄生された患者はしばしば関連した胃萎縮を起こす。[[blind loop syndrome/ja|ブラインドループ症候群]]はビタミンB<sub>12</sub>または[[folate/ja|葉酸]]の欠乏を引き起こすことがある。 * ビタミンB<sub>12</sub>の不十分な使用は、[[neoplasia/ja|新生物]]の治療にビタミンB<sub>12</sub>の[[antimetabolites/ja|代謝拮抗薬]]が使用されている場合に起こりうる。 [[Pernicious anemia/ja|悪性貧血]]はビタミンB<sub>12</sub>欠乏の最も一般的な原因である。厳密には内因性因子の自己免疫性欠乏によって特異的に起こる貧血を指すが、一般的には原因に関係なくB<sub>12</sub>欠乏性貧血全体を指す。 |