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NameCurrent message text
 h English (en)====Subcellular distribution====
Enzymes can be compartmentalized, with different metabolic pathways occurring in different [[cellular compartment]]s. For example, [[fatty acid]]s are synthesized by one set of enzymes in the [[cytosol]], [[endoplasmic reticulum]] and [[golgi apparatus|Golgi]] and used by a different set of enzymes as a source of energy in the [[mitochondrion]], through [[β-oxidation]]. In addition, [[protein targeting|trafficking]] of the enzyme to different compartments may change the degree of [[protonation]] (e.g., the neutral [[cytoplasm]] and the acidic [[lysosome]]) or oxidative state (e.g., oxidizing [[periplasm]] or reducing [[cytoplasm]]) which in turn affects enzyme activity. In contrast to partitioning into membrane bound organelles, enzyme subcellular localisation may also be altered through polymerisation of enzymes into macromolecular cytoplasmic filaments.
 h Japanese (ja)====細胞内分布====
酵素はコンパートメント化することができ、異なる代謝経路が異なる[[cellular compartment/ja|細胞コンパートメント]]で起こる。例えば、[[fatty acid/ja|脂肪酸]]は[[cytosol/ja|細胞質]]、[[endoplasmic reticulum/ja|小胞体]]、[[golgi apparatus/ja|ゴルジ体]]で1組の酵素によって合成され、[[mitochondrion/ja|ミトコンドリア]]では[[β-oxidation/ja|β-酸化]]によってエネルギー源として別の1組の酵素によって利用される。さらに、酵素の[[protein targeting/ja|取引]]によって、[[protonation/ja|プロトン化]]の程度(例えば、中性の[[cytoplasm/ja|細胞質]]と酸性の[[lysosome/ja|リソソーム]])や酸化状態(例えば、酸化的な[[periplasm/ja|ペリプラズム]]や還元的な[[cytoplasm/ja|細胞質]])が変化し、それが酵素活性に影響を与えることもある。膜結合オルガネラへの分配とは対照的に、酵素の細胞内局在は、高分子細胞質フィラメントへの酵素の重合によって変化することもある。