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 h English (en)==DPP-4 mechanism==
[[File:Inhibition of DPP-4 enzyme.JPG|thumb|350px]]'''Fig.1:''' During a [[meal]], the [[incretin]]s [[glucagon-like peptide 1]] (GLP-1) and glucose-dependent [[gastric inhibitory polypeptide]] (GIP) are released by the [[small intestine]] into the blood stream. These [[hormone]]s regulate insulin secretion in a glucose-dependent manner. (GLP-1 has many roles in the [[human body]]. It stimulates insulin biosynthesis, inhibits glucagon secretion, slows gastric emptying, reduces appetite and stimulates regeneration of islet [[Beta cell|β-cell]]s.)
 h Japanese (ja)==DPP-4のメカニズム==
{{Anchor|DPP-4 mechanism}}
[[File:Inhibition of DPP-4 enzyme.JPG|thumb|350px]]
'''図1:''''[[meal/ja|食事]]中に、[[incretin/ja|インクレチン]]である[[glucagon-like peptide 1/ja|グルカゴン様ペプチド1]](GLP-1)とグルコース依存性[[gastric inhibitory polypeptide/ja|胃抑制ポリペプチド]](GIP)が[[small intestine/ja|小腸]]から血液中に放出される。これらの[[hormone/ja|ホルモン]]はグルコース依存的にインスリン分泌を調節する。(GLP-1は[[human body/ja|人体]]において多くの役割を持っている。インスリンの生合成を刺激し、グルカゴンの分泌を抑制し、胃排出を遅らせ、食欲を減退させ、膵島[[beta cell/ja|β-cell]]の再生を刺激する)