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Found 2 translations.
| Name | Current message text |
|---|---|
| h English (en) | Saralasin was developed in the early 1970s and is an octapeptide analogue of Ang II, where the [[amino acids]] [[Aspartic acid|Asp]]<sup>1</sup>, [[Isoleucine|Ile]]<sup>5</sup> and [[Phenylalanine|Phe]]<sup>8</sup> have been replaced with [[Serine|Ser]]<sup>1</sup>, [[Valine|Val]]<sup>5</sup> and [[Alanine|Ala]]<sup>8</sup>, respectively. Saralasin was not orally [[bioavailable]], had short duration of action and showed [[partial agonist]] activity and therefore it was not suitable as a drug. |
| h Japanese (ja) | サララシンは1970年代初頭に開発され、Ang IIのオクタペプチドアナログである。[[Aspartic acid/ja|Asp]]<sup>1</sup>、[[Isoleucine/ja|Ile]]<sup>5</sup>、[[Phenylalanine/ja|Phe]]<sup>8</sup>がそれぞれ[[Serine/ja|Ser]]<sup>1</sup>、[[Valine/ja|Val]]<sup>5</sup>、[[Alanine/ja|Ala]]<sup>8</sup>に置き換えられている。サララシンは経口[[bioavailable/ja|生物学的利用能]]がなく、作用時間が短く、[[partial agonist/ja|部分作動薬]]活性を示したため、薬物としては適さなかった。 |