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Found 2 translations.
| Name | Current message text |
|---|---|
| h English (en) | {| class="wikitable" | '''Family''' || '''Function''' || '''Members''' || '''Genes''' || '''Pseudogenes''' |- | '''CYP1''' || drug and steroid (especially [[estrogen]]) metabolism, [[benzo(a)pyrene|benzo[''a'']pyrene]] toxification (forming [[(+)-Benzo(a)pyrene-7,8-dihydrodiol-9,10-epoxide|(+)-benzo[''a'']pyrene-7,8-dihydrodiol-9,10-epoxide]]) || 3 subfamilies, 3 genes, 1 [[pseudogene]] || [[CYP1A1]], [[CYP1A2]], [[CYP1B1]] || [[CYP1D1P]] |- | '''CYP2''' || drug and [[steroid]] metabolism || 13 subfamilies, 16 genes, 16 [[pseudogene]]s || [[CYP2A6]], [[CYP2A7]], [[CYP2A13]], [[CYP2B6]], [[CYP2C8]], [[CYP2C9]], [[CYP2C18]], [[CYP2C19]], [[CYP2D6]], [[CYP2E1]], [[CYP2F1]], [[CYP2J2]], [[CYP2R1]], [[CYP2S1]], [[CYP2U1]], [[CYP2W1]] || Too many to list |- | '''CYP3''' || drug and [[steroid]] (including [[testosterone]]) metabolism || 1 subfamily, 4 genes, 4 [[pseudogene]]s || [[CYP3A4]], [[CYP3A5]], [[CYP3A7]], [[CYP3A43]] || CYP3A51P, CYP3A52P, CYP3A54P, CYP3A137P |- | '''CYP4''' || [[arachidonic acid]] or fatty acid metabolism || 6 subfamilies, 12 genes, 10 [[pseudogene]]s || [[CYP4A11]], [[CYP4A22]], [[CYP4B1]], [[CYP4F2]], [[CYP4F3]], [[CYP4F8]], [[CYP4F11]], [[CYP4F12]], [[CYP4F22]], [[CYP4V2]], [[CYP4X1]], [[CYP4Z1]] || Too many to list |- | '''CYP5''' || [[thromboxane]] A<sub>2</sub> [[thromboxane-A synthase|synthase]] || 1 subfamily, 1 gene || [[Thromboxane-A synthase|CYP5A1]] || |- | '''CYP7''' || [[bile acid]] biosynthesis 7-alpha hydroxylase of steroid nucleus || 2 subfamilies, 2 genes || [[CYP7A1]], [[CYP7B1]] || |- | '''CYP8''' || ''varied'' || 2 subfamilies, 2 genes || [[CYP8A1]] ([[prostacyclin]] synthase), [[CYP8B1]] (bile acid biosynthesis) || |- | '''CYP11''' || [[steroid]] biosynthesis || 2 subfamilies, 3 genes || [[CYP11A1]], [[CYP11B1]], [[CYP11B2]] || |- | '''CYP17''' || [[steroid]] biosynthesis, 17-alpha hydroxylase || 1 subfamily, 1 gene || [[CYP17A1]] || |- | '''CYP19''' || [[steroid]] biosynthesis: [[aromatase]] synthesizes [[estrogen]] || 1 subfamily, 1 gene || [[CYP19A1]] || |- | '''CYP20''' || unknown function || 1 subfamily, 1 gene || [[CYP20A1]] || |- | '''CYP21''' || [[steroid]] biosynthesis || 1 subfamilies, 1 gene, 1 pseudogene || [[CYP21A2]] || [[CYP21A1P]] |- | '''CYP24''' || [[vitamin D]] degradation || 1 subfamily, 1 gene || [[CYP24A1]] || |- | '''[[CYP26]]''' || [[retinoic acid]] hydroxylase || 3 subfamilies, 3 genes || [[CYP26A1]], [[CYP26B1]], [[CYP26C1]] || |- | '''CYP27''' || ''varied'' || 3 subfamilies, 3 genes || [[CYP27A1]] ([[bile acid]] biosynthesis), [[CYP27B1]] (vitamin D<sub>3</sub> 1-alpha hydroxylase, activates vitamin D<sub>3</sub>), [[CYP27C1]] (vitamin A1 to A2) || |- | '''CYP39''' || 7-alpha hydroxylation of 24-hydroxycholesterol || 1 subfamily, 1 gene || [[CYP39A1]] || |- | '''CYP46''' || [[cholesterol]] 24-hydroxylase || 1 subfamily, 1 gene, 1 pseudogene || [[CYP46A1]] || CYP46A4P |- | '''CYP51''' || [[cholesterol]] biosynthesis || 1 subfamily, 1 gene, 3 pseudogenes || [[CYP51A1]] ([[lanosterol]] 14-alpha demethylase) || CYP51P1, CYP51P2, CYP51P3 |} |
| h Japanese (ja) | {| class="wikitable" | '''ファミリー''' || '''機能''' || '''メンバー''' || '''遺伝子''' || '''偽遺伝子''' |- | '''CYP1''' || 薬物およびステロイド（特に[[estrogen/ja|エストロゲン]]）の代謝、[[benzo(a)pyrene/ja|ベンゾ[''a'']ピレン]]の毒化（[[(+)-Benzo(a)pyrene-7,8-dihydrodiol-9,10-epoxide/ja|(+)-ベンゾ[''a'']ピレン-7,8-ジヒドロジオール-9,10-エポキシド]]を形成する） || 3サブファミリー、3遺伝子、1[[pseudogene/ja|偽遺伝子]] || [[CYP1A1/ja|CYP1A1]], [[CYP1A2/ja|CYP1A2]], [[CYP1B1/ja|CYP1B1]] || [[CYP1D1P/ja|CYP1D1P]] |- | '''CYP2''' || 薬物および[[steroid/ja|ステロイド]]の代謝 || 13サブファミリー, 16遺伝子, 16 [[pseudogene/ja|偽遺伝子]] || [[CYP2A6/ja|CYP2A6]], [[CYP2A7/ja|CYP2A7]], [[CYP2A13/ja|CYP2A13]], [[CYP2B6/ja|CYP2B6]], [[CYP2C8/ja|CYP2C8]], [[CYP2C9/ja|CYP2C9]], [[CYP2C18/ja|CYP2C18]], [[CYP2C19/ja|CYP2C19]], [[CYP2D6/ja|CYP2D6]], [[CYP2E1/ja|CYP2E1]], [[CYP2F1/ja|CYP2F1]], [[CYP2J2/ja|CYP2J2]], [[CYP2R1/ja|CYP2R1]], [[CYP2S1/ja|CYP2S1]], [[CYP2U1/ja|CYP2U1]], [[CYP2W1/ja|CYP2W1]] || 枚挙にいとまがない |- | '''CYP3''' || 薬物と[[steroid/ja|ステロイド]] ([[testosterone/ja|テストステロン]]を含む) の代謝 || 1サブファミリー, 4遺伝子, 4[[pseudogene/ja|偽遺伝子]] || [[CYP3A4/ja|CYP3A4]], [[CYP3A5/ja|CYP3A5]], [[CYP3A7/ja|CYP3A7]], [[CYP3A43/ja|CYP3A43]] || CYP3A51P, CYP3A52P, CYP3A54P, CYP3A137P |- | '''CYP4''' || [[arachidonic acid/ja|アラキドン酸]]あるいは脂肪酸代謝 || 6サブファミリー, 12遺伝子, 10[[pseudogene/ja|偽遺伝子]] || [[CYP4A11/ja|CYP4A11]], [[CYP4A22/ja|CYP4A22]], [[CYP4B1/ja|CYP4B1]], [[CYP4F2/ja|CYP4F2]], [[CYP4F3/ja|CYP4F3]], [[CYP4F8/ja|CYP4F8]], [[CYP4F11/ja|CYP4F11]], [[CYP4F12/ja|CYP4F12]], [[CYP4F22/ja|CYP4F22]], [[CYP4V2/ja|CYP4V2]], [[CYP4X1/ja|CYP4X1]], [[CYP4Z1/ja|CYP4Z1]] || 枚挙にいとまがない |- | '''CYP5''' || [[thromboxane/ja|トロンボキサン]] A<sub>2</sub> [[thromboxane-A synthase/ja|合成]] || 1サブファミリー, 1遺伝子 || [[Thromboxane-A synthase/ja|CYP5A1]] || |- | '''CYP7''' || [[bile acid/ja|胆汁酸]]生合成 ステロイド核の7α水酸化酵素 || 2サブファミリー, 2遺伝子 || [[CYP7A1/ja|CYP7A1]], [[CYP7B1/ja|CYP7B1]] || |- | '''CYP8''' || ''さまざま'' || 2サブファミリー, 2遺伝子 || [[CYP8A1/ja|CYP8A1]] ([[prostacyclin/ja|プロスタサイクリン]]合成酵素), [[CYP8B1/ja|CYP8B1]] (胆汁酸生合成) || |- | '''CYP11''' || [[steroid/ja|ステロイド]]生合成 || 2サブファミリー, 3遺伝子 || [[CYP11A1/ja|CYP11A1]], [[CYP11B1/ja|CYP11B1]], [[CYP11B2/ja|CYP11B2]] || |- | '''CYP17''' || [[steroid/ja|ステロイド]]生合成、17α水酸化酵素 || 1サブファミリー, 1遺伝子 || [[CYP17A1/ja|CYP17A1]] || |- | '''CYP19''' || [[steroid/ja|ステロイド]]生合成、17α水酸化酵素: [[aromatase/ja|アロマターゼ]]は[[estrogen/ja|エストロゲン]]を合成する。 || 1サブファミリー, 1遺伝子 || [[CYP19A1/ja|CYP19A1]] || |- | '''CYP20''' || 機能不明 || 1サブファミリー, 1遺伝子 || [[CYP20A1/ja|CYP20A1]] || |- | '''CYP21''' || [[steroid/ja|ステロイド]]生合成 || 1サブファミリー, 1遺伝子, 1偽遺伝子 || [[CYP21A2/ja|CYP21A2]] || [[CYP21A1P/ja|CYP21A1P]] |- | '''CYP24''' || [[vitamin D/ja]]劣化 || 1サブファミリー, 1遺伝子 || [[CYP24A1/ja|CYP24A1]] || |- | '''[[CYP26/ja|CYP26]]''' || [[retinoic acid/ja|レチノイン酸]]水酸化酵素 || 3サブファミリー, 3遺伝子 || [[CYP26A1/ja|CYP26A1]], [[CYP26B1/ja|CYP26B1]], [[CYP26C1/ja|CYP26C1]] || |- | '''CYP27''' || ''さまざま'' || 3サブファミリー, 3遺伝子 || [[CYP27A1/ja|CYP27A1]] ([[bile acid/ja|胆汁酸]]生合成), [[CYP27B1/ja|CYP27B1]] (ビタミンD<sub>3</sub> 1-α水酸化酵素、ビタミンD<sub>3</sub>を活性化する), [[CYP27C1/ja|CYP27C1]] (ビタミンA1からA2へ) || |- | '''CYP39''' || 24-ヒドロキシコレステロールの7α水酸化反応 || 1サブファミリー, 1遺伝子 || [[CYP39A1/ja|CYP39A1]] || |- | '''CYP46''' || [[cholesterol/ja|コレステロール]]24-水酸化酵素 || 1サブファミリー, 1遺伝子, 1偽遺伝子 || [[CYP46A1/ja|CYP46A1]] || CYP46A4P |- | '''CYP51''' || [[cholesterol/ja|コレステロール]]生合成 || 1サブファミリー, 1遺伝子, 3偽遺伝子 || [[CYP51A1/ja|CYP51A1]] ([[lanosterol/ja|ラノステロール]] 14α脱メチル化酵素) || CYP51P1, CYP51P2, CYP51P3 |} |