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Found 2 translations.
| Name | Current message text |
|---|---|
| h English (en) | ====Drug interaction==== Many drugs may increase or decrease the activity of various P450 [[isozyme]]s either by inducing the biosynthesis of an isozyme ([[Regulation of gene expression|enzyme induction]]) or by directly inhibiting the activity of the P450 ([[enzyme inhibition]]). A classical example includes [[Anticonvulsant|anti-epileptic drugs]], such as [[phenytoin]], which induces [[CYP1A2]], [[CYP2C9]], [[CYP2C19]], and [[CYP3A4]]. |
| h Japanese (ja) | ===薬物相互作用=== 多くの薬物は、アイソザイムの生合成を誘導する（[[Regulation of gene expression/ja|酵素誘導]]）か、P450の活性を直接阻害する（[[enzyme inhibition/ja|酵素阻害]]）かのどちらかによって、様々なP450[[isozyme/ja|アイソザイム]]の活性を増減させる可能性がある。古典的な例としては、[[CYP1A2/ja|CYP1A2]]、[[CYP2C9/ja|CYP2C9]]、[[CYP2C19/ja|CYP2C19]]、[[CYP3A4/ja|CYP3A4]]を誘導する[[phenytoin/ja|フェニトイン]]などの[[Anticonvulsant/ja|抗てんかん薬]]が挙げられる。 |