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Found 2 translations.
| Name | Current message text |
|---|---|
| h English (en) | In the liver, the carboxylation of [[cytosol]]ic pyruvate into intra-mitochondrial ''oxaloacetate'' is an early step in the [[gluconeogenesis|gluconeogenic]] pathway which converts [[lactic acid|lactate]] and de-aminated [[alanine]] into glucose, under the influence of high levels of [[glucagon]] and/or [[epinephrine]] in the blood. Here the addition of ''oxaloacetate'' to the mitochondrion does not have a net anaplerotic effect, as another citric acid cycle intermediate (''malate'') is immediately removed from the mitochondrion to be converted into cytosolic oxaloacetate, which is ultimately converted into glucose, in a process that is almost the reverse of [[glycolysis]]. |
| h Japanese (ja) | 肝臓では、[[cytosol/ja|細胞質]]のピルビン酸のミトコンドリア内''オキサロ酢酸''へのカルボキシル化は、血中の高レベルの[[glucagon/ja|グルカゴン]]および/または[[epinephrine/ja|エピネフリン]]の影響下で、[[lactic acid/ja|乳酸]]と脱アミノ化[[alanine/ja|アラニン]]をグルコースに変換する[[gluconeogenesis/ja|糖新生]]経路の初期段階である。ここで''オキサロ酢酸''をミトコンドリアに添加しても、別のクエン酸サイクル中間体（''リンゴ酸''）が直ちにミトコンドリアから除去されて細胞質オキサロ酢酸に変換され、最終的にグルコースに変換されるため、[[glycolysis/ja|解糖]]とはほぼ逆のプロセスで、正味のアナプラローシス効果はない。 |