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Found 2 translations.
| Name | Current message text |
|---|---|
| h English (en) | Recombinant therapeutic [[proteins]] are of a complex nature (composed of a long chain of amino acids, modified amino acids, derivatized by sugar moieties, folded by complex mechanisms). These proteins are made in living cells (bacteria, yeast, animal or human cell lines). The ultimate characteristics of a drug containing a recombinant therapeutic protein are to a large part determined by the process through which they are produced: choice of the cell type, development of the genetically modified cell for production, production process, purification process, formulation of the therapeutic protein into a drug. |
| h Japanese (ja) | 組換え治療用[[proteins/ja|タンパク質]]は、複雑な性質（アミノ酸の長鎖、修飾アミノ酸、糖鎖による誘導体化、複雑なメカニズムによる折り畳み）を持つ。これらのタンパク質は、生きた細胞（細菌、酵母、動物またはヒトの細胞株）で作られる。組換え治療用タンパク質を含む薬物の最終的な特性は、それらが生産される過程（細胞の種類の選択、生産のための遺伝子組換え細胞の開発、生産過程、精製過程、治療用タンパク質の薬物への製剤化）によって大きく左右される。 |