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Found 2 translations.
| Name | Current message text |
|---|---|
| h English (en) | From human clinical trials, it has become increasingly evident that a more effective focus of treatment is slowing, stopping and even partially reversing the atheroma growth process. There are several prospective epidemiologic studies including the [[Atherosclerosis Risk in Communities|Atherosclerosis Risk in Communities (ARIC) Study]] and the Cardiovascular Health Study (CHS), which have supported a direct correlation of [[Carotid]] [[Intima-media thickness]] (CIMT) with myocardial infarction and stroke risk in patients without cardiovascular disease history. The ARIC Study was conducted in 15,792 individuals between 5 and 65 years of age in four different regions of the US between 1987 and 1989. The baseline CIMT was measured and measurements were repeated at 4- to 7-year intervals by carotid B mode ultrasonography in this study. An increase in CIMT was correlated with an increased risk for CAD. The CHS was initiated in 1988, and the relationship of CIMT with risk of myocardial infarction and stroke was investigated in 4,476 subjects 65 years of age and below. At the end of approximately six years of follow-up, CIMT measurements were correlated with cardiovascular events. |
| h Japanese (ja) | ヒトの臨床試験から、より効果的な治療の焦点は、粥腫の成長過程を遅らせたり、止めたり、さらには部分的に逆転させることであることが次第に明らかになってきた。[[Carotid/ja|頸動脈]][[Intima-media thickness/ja|内膜中膜厚]]（CIMT）と心筋梗塞の直接的な相関を支持した[[:en:Atherosclerosis Risk in Communities|地域社会における動脈硬化リスク（ARIC）研究]]や[[:en:Cardiovascular Health Study (CHS)|心血管健康調査（CHS）]]などのいくつかの前向き疫学研究がある。ARIC研究は、1987年から1989年にかけて、米国の4つの異なる地域の5歳から65歳の15,792人を対象に実施された。この研究では、ベースラインのCIMTが測定され、頸動脈Bモード超音波検査によって4〜7年間隔で測定が繰り返された。CIMTの増加はCADリスクの増加と相関していた。CHSは1988年に開始され、65歳以下の4,476人を対象にCIMTと心筋梗塞および脳卒中のリスクとの関係が調査された。約6年間の追跡調査終了時、CIMT測定値は心血管イベントと相関していた。 |