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Found 2 translations.
| Name | Current message text |
|---|---|
| h English (en) | However, ACE inhibitors (and angiotensin II receptor antagonists) should not be a first-line treatment for black hypertensives without [[chronic kidney disease]]. Results from the [[Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial|ALLHAT]] trial showed that [[thiazide]]-type diuretics and calcium channel blockers were both more effective as monotherapy in improving cardiovascular outcomes compared to ACE inhibitors for this subgroup. Furthermore, ACE inhibitors were less effective in reducing blood pressure and had a 51% higher risk of stroke in black hypertensives when used as initial therapy compared to a calcium channel blocker. There are fixed-dose [[combination drugs]], such as [[ACE inhibitor and thiazide combination]]s. |
| h Japanese (ja) | しかし、ACE阻害薬（およびアンジオテンシンII受容体拮抗薬）は[[chronic kidney disease/ja|慢性腎臓病]]のない黒人の高血圧患者には第一選択薬とすべきではない。[[Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial/ja|ALLHAT]]試験の結果では、このサブグループではACE阻害薬よりもサイアザイド系利尿薬とカルシウム拮抗薬の単剤療法の方が心血管予後の改善に有効であった。さらに、ACE阻害薬はカルシウム拮抗薬と比較して、初回治療として使用した場合、黒人の高血圧患者では血圧降下効果が低く、脳卒中のリスクが51％高かった。[[ACE inhibitor and thiazide/ja|ACE阻害薬とサイアザイド系薬剤の合剤]]のような[[combination drugs/ja|配合薬]]もある。 |