Antidiarrheal: Difference between revisions

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* [[Opioid]]s' classical use besides pain relief is as an anti-diarrhoeal drug. Opioids have [[agonist]] actions on the intestinal opioid receptors, which when activated cause [[constipation]]. Drugs such as [[morphine]] or [[codeine]] can be used to relieve diarrhoea this way. A notable opioid for the purpose of relief of diarrhoea is [[loperamide]] which is only an agonist of the [[mu Opioid receptor|μ opioid receptor]]s in the large intestine and does not have opioid affects in the [[central nervous system]] as it doesn't cross the [[blood–brain barrier]] in significant amounts. This enables loperamide to be used to the same benefit as other opioid drugs but without the CNS side effects or potential for abuse.

*[[Octreotide]] (somatostatin analogue) may be used in hospitalized patients to treat secretory diarrhea.

* [[Probiotics]] are commonly given to breastfeeding mothers and their young children to prevent eczema ([[dermatitis]]), but no good evidence shows efficacy for this purpose. There is little evidence to support the use of probiotics to treat [[atopic dermatitis]], and some risk of [[adverse effect]]s.

==See also==

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 * [[Opioid]]s' classical use besides pain relief is as an anti-diarrhoeal drug. Opioids have [[agonist]] actions on the intestinal opioid receptors, which when activated cause [[constipation]]. Drugs such as [[morphine]] or [[codeine]] can be used to relieve diarrhoea this way. A notable opioid for the purpose of relief of diarrhoea is [[loperamide]] which is only an agonist of the [[mu Opioid receptor|μ opioid receptor]]s in the large intestine and does not have opioid affects in the [[central nervous system]] as it doesn't cross the [[blood–brain barrier]] in significant amounts. This enables loperamide to be used to the same benefit as other opioid drugs but without the CNS side effects or potential for abuse.
 *[[Octreotide]] (somatostatin analogue) may be used in hospitalized patients to treat secretory diarrhea.
+* [[Probiotics]] are commonly given to breastfeeding mothers and their young children to prevent eczema ([[dermatitis]]), but no good evidence shows efficacy for this purpose. There is little evidence to support the use of probiotics to treat [[atopic dermatitis]], and some risk of [[adverse effect]]s.
 ==See also==