Calcitriol/ja: Difference between revisions

Calcitriol/ja
Created page with "<!-- Chemical and physical data --> | IUPAC_name = (1''R'',3''S'')-5-[2-[(1''R'',3a''R'',7a''S'')-1-[(2''R'')-6-hydroxy-6-methyl-heptan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1''H''- inden-4-ylidene]ethylidene]-4-methylidene-cyclohexane-1,3-diol | C=27 | H=44 | O=3 | SMILES = C[C@H](CCCC(C)(C)O)[C@H]1CC[C@@H]\2[C@@]1(CCC/C2=C\C=C/3\C[C@H](C[C@@H](C3=C)O)O)C | StdInChI_Ref = {{stdinchicite|correct|chemspider}} | StdInChI = 1S/C27H44O3/c1-18(8-6-14-26(3,4)30)23-12-13-24-20..."
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<!-- Definition and physiology -->
<!-- Definition and physiology -->
'''Calcitriol''' is the active form of [[vitamin D]], normally made in the [[kidney]]. It is also known as '''1,25-dihydroxycholecalciferol'''. It is a [[hormone]] which binds to and activates the [[vitamin D receptor]] in the nucleus of the cell, which then increases the expression of many genes. Calcitriol increases blood [[Calcium in biology|calcium]] (Ca<sup>2+</sup>) mainly by increasing the uptake of calcium from the [[intestines]].
'''カルシトリオール'''[[vitamin D/ja|ビタミンD]]の活性型であり、通常は[[kidney/ja|腎臓]]で作られる。別名'''1,25-ジヒドロキシコレカルシフェロール'''とも呼ばれる。カルシトリオールは[[hormone/ja|ホルモン]]であり、細胞核内の[[vitamin D receptor/ja|ビタミンD受容体]]に結合して活性化し、多くの遺伝子の発現を増加させる。カルシトリオールは、主に[[intestines/ja|腸]]からのカルシウムの取り込みを増加させることによって、血液中の[[Calcium in biology/ja|生物におけるカルシウム]](Ca<sup>2+</sup>)を増加させる。
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{{二次利用|date=20 March 2024}}
[[Category:Wikipedia medicine articles ready to translate]]
[[Category:Wikipedia medicine articles ready to translate]]
[[Category:Secosteroids]]
[[Category:Secosteroids]]
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[[Category:Drugs developed by Hoffmann-La Roche]]
[[Category:Drugs developed by Hoffmann-La Roche]]
[[Category:World Health Organization essential medicines]]
[[Category:World Health Organization essential medicines]]
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