Methylcobalamin: Difference between revisions

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Methylcobalamin participates in the [[Wood-Ljungdahl pathway]], which is a pathway by which some organisms utilize carbon dioxide as their source of organic compounds. In this pathway, methylcobalamin provides the methyl group that couples to carbon monoxide (derived from CO2) to afford [[acetyl-CoA]]. Acetyl-CoA is a derivative of acetic acid that is converted to more complex molecules as required by the organism.

Methylcobalamin is produced by some [[bacteria]].~~{{cn|date=February 2021}}~~ It plays an important role in the environment, where it is responsible for the [[biomethylation]] of certain [[heavy metal (chemistry)|heavy metal]]s. For example, the highly toxic [[methylmercury]] is produced by the action of methylcobalamin. In this role, methylcobalamin serves as a source of "CH3+".

Methylcobalamin is produced by some [[bacteria]]. It plays an important role in the environment, where it is responsible for the [[biomethylation]] of certain [[heavy metal (chemistry)|heavy metal]]s. For example, the highly toxic [[methylmercury]] is produced by the action of methylcobalamin. In this role, methylcobalamin serves as a source of "CH3+".

A lack of cobalamin can lead to [[megaloblastic anemia]] and subacute combined degeneration of the spinal cord.

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 Methylcobalamin participates in the [[Wood-Ljungdahl pathway]], which is a pathway by which some organisms utilize carbon dioxide as their source of organic compounds.  In this pathway, methylcobalamin provides the methyl group that couples to carbon monoxide (derived from CO<sub>2</sub>) to afford [[acetyl-CoA]].  Acetyl-CoA is a derivative of acetic acid that is converted to more complex molecules as required by the organism.
-Methylcobalamin is produced by some [[bacteria]].{{cn|date=February 2021}} It plays an important role in the environment, where it is responsible for the [[biomethylation]] of certain [[heavy metal (chemistry)|heavy metal]]s.  For example, the highly toxic [[methylmercury]] is produced by the action of methylcobalamin.  In this role, methylcobalamin serves as a source of "CH<sub>3</sub><sup>+</sup>".
+Methylcobalamin is produced by some [[bacteria]]. It plays an important role in the environment, where it is responsible for the [[biomethylation]] of certain [[heavy metal (chemistry)|heavy metal]]s.  For example, the highly toxic [[methylmercury]] is produced by the action of methylcobalamin.  In this role, methylcobalamin serves as a source of "CH<sub>3</sub><sup>+</sup>".
 A lack of cobalamin can lead to [[megaloblastic anemia]] and subacute combined degeneration of the spinal cord.