Glucagon-like peptide-1: Difference between revisions
Created page with "{{Short description|Gastrointestinal peptide hormone Involved in glucose homeostasis}} thumb|350px|right|GLP-1 and diabetes '''Glucagon-like peptide-1''' ('''GLP-1''') is a 30- or 31-amino-acid-long peptide hormone deriving from the tissue-specific posttranslational processing of the proglucagon peptide. It is produced and secreted by intestinal enteroendocrine L-cells and certain neurons with..." |
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==Physiological functions== | ==Physiological functions== | ||
GLP-1 possesses several physiological properties making it (and its [[Functional analog (chemistry)|functional analog]]s) a subject of intensive investigation as a potential treatment of [[diabetes mellitus]], as these actions induce long-term improvements along with the immediate effects. Although reduced GLP-1 secretion has previously been associated with attenuated incretin effect in patients with [[type 2 diabetes]], it is now granted that GLP-1 secretion in patients with type 2 diabetes does not differ from healthy subjects. | GLP-1 possesses several physiological properties making it (and its [[Functional analog (chemistry)|functional analog]]s) a subject of intensive investigation as a potential treatment of [[diabetes mellitus]], as these actions induce long-term improvements along with the immediate effects. Although reduced GLP-1 secretion has previously been associated with attenuated incretin effect in patients with [[type 2 diabetes]], it is now granted that GLP-1 secretion in patients with type 2 diabetes does not differ from healthy subjects. | ||
