Vitamin B3: Difference between revisions
Vitamin B3
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== Toxicity == | == Toxicity == | ||
The daily limit for vitamin B<sub>3</sub> has been set at 35 mg. At daily doses of as low as 30 mg, flushing has been reported, always starting in the face and sometimes accompanied by skin dryness, itching, paresthesia, and headache. Liver toxicity is the most serious toxic reaction and it occurs at doses >2 grams/day. [[Fulminant hepatitis]] has been reported at doses between 3-9 grams/day with needs for liver transplantation. | The daily limit for vitamin B<sub>3</sub> has been set at 35 mg. At daily doses of as low as 30 mg, flushing has been reported, always starting in the face and sometimes accompanied by skin dryness, itching, paresthesia, and headache. Liver toxicity is the most serious toxic reaction and it occurs at doses >2 grams/day. [[Fulminant hepatitis]] has been reported at doses between 3-9 grams/day with needs for liver transplantation. Other reactions include [[Impaired glucose tolerance|glucose intolerance]], [[hyperuricemia]], [[macular edema]], and [[macular cysts]]. | ||
== History == | == History == | ||