Fursultiamine: Difference between revisions
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Created page with "<languages /> <translate> {{Short description|Chemical compound}} {{Drugbox | IUPAC_name = ''N''-[(4-Amino-2-methylpyrimidin-5-yl)methyl]-''N''-<nowiki>{</nowiki>(1''E'')-4-hydroxy-1-methyl-2-[(tetrahydrofuran-2-ylmethyl)disulfanyl]but-1-en-1-yl}formamide | image = Fursultiamine.png | alt = Skeletal formula of fursultiamine | width = 200 | image2 = Fursultiamine 3D ball.png | alt2 = Ball-and-stick model of the fursultiamine molecule | width2 = 200 <!--Clinical data--> |..." |
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'''Fursultiamine''' ([[International Nonproprietary Name|INN]]; chemical name '''thiamine tetrahydrofurfuryl disulfide''' or '''TTFD'''; brand names '''Adventan''', '''Alinamin-F''', '''Benlipoid''', '''Bevitol Lipophil''', '''Judolor''', '''Lipothiamine''') is a medication and vitamin used to treat [[thiamine]] deficiency. Chemically, it is a [[disulfide]] [[derivative (chemistry)|derivative]] of thiamine and is similar in structure to [[allithiamine]]. | '''Fursultiamine''' ([[International Nonproprietary Name|INN]]; chemical name '''thiamine tetrahydrofurfuryl disulfide''' or '''TTFD'''; brand names '''Adventan''', '''Alinamin-F''', '''Benlipoid''', '''Bevitol Lipophil''', '''Judolor''', '''Lipothiamine''') is a medication and vitamin used to treat [[thiamine]] deficiency. Chemically, it is a [[disulfide]] [[derivative (chemistry)|derivative]] of thiamine and is similar in structure to [[allithiamine]]. | ||
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It was synthesized in [[Japan]] in the 1960s from [[allithiamine]] for the purpose of developing forms of thiamine with improved [[lipophilicity]] for treating [[Thiamine#Deficiency|vitamin B<sub>1</sub> deficiency]] (i.e., [[beriberi]]), It was subsequently commercialized not only in Japan but also in [[Spain]], [[Austria]], [[Germany]], and the [[United States]]. | It was synthesized in [[Japan]] in the 1960s from [[allithiamine]] for the purpose of developing forms of thiamine with improved [[lipophilicity]] for treating [[Thiamine#Deficiency|vitamin B<sub>1</sub> deficiency]] (i.e., [[beriberi]]), It was subsequently commercialized not only in Japan but also in [[Spain]], [[Austria]], [[Germany]], and the [[United States]]. | ||
== See also == | == See also == <!--T:8--> | ||
* [[Vitamin B1 analogue|Vitamin B<sub>1</sub> analogue]] | * [[Vitamin B1 analogue|Vitamin B<sub>1</sub> analogue]] | ||
== Further reading == | == Further reading == <!--T:9--> | ||
* {{cite journal | vauthors = Lonsdale D | title = Thiamine tetrahydrofurfuryl disulfide: a little known therapeutic agent | journal = Medical Science Monitor | volume = 10 | issue = 9 | pages = RA199–203 | date = September 2004 | pmid = 15328496 | url = http://www.medscimonit.com/fulltxt.php?ICID=11763 }} | * {{cite journal | vauthors = Lonsdale D | title = Thiamine tetrahydrofurfuryl disulfide: a little known therapeutic agent | journal = Medical Science Monitor | volume = 10 | issue = 9 | pages = RA199–203 | date = September 2004 | pmid = 15328496 | url = http://www.medscimonit.com/fulltxt.php?ICID=11763 }} | ||
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{{Vitamins}} | {{Vitamins}} | ||
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{{二次利用|date=6 April 2023}} | {{二次利用|date=6 April 2023}} | ||
[[Category:Formamides]] | [[Category:Formamides]] | ||
Latest revision as of 09:39, 3 April 2024
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| AHFS/Drugs.com | International Drug Names |
| Routes of administration | Oral |
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| Formula | C17H26N4O3S2 |
| Molar mass | 398.54 g·mol−1 |
| 3D model (JSmol) | |
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Fursultiamine (INN; chemical name thiamine tetrahydrofurfuryl disulfide or TTFD; brand names Adventan, Alinamin-F, Benlipoid, Bevitol Lipophil, Judolor, Lipothiamine) is a medication and vitamin used to treat thiamine deficiency. Chemically, it is a disulfide derivative of thiamine and is similar in structure to allithiamine.
It was synthesized in Japan in the 1960s from allithiamine for the purpose of developing forms of thiamine with improved lipophilicity for treating vitamin B1 deficiency (i.e., beriberi), It was subsequently commercialized not only in Japan but also in Spain, Austria, Germany, and the United States.
See also
Further reading
- Lonsdale D (September 2004). "Thiamine tetrahydrofurfuryl disulfide: a little known therapeutic agent". Medical Science Monitor. 10 (9): RA199–203. PMID 15328496.
 | この記事は、クリエイティブ・コモンズ・表示・継承ライセンス3.0のもとで公表されたウィキペディアの項目Fursultiamine(6 April 2023編集記事参照)を素材として二次利用しています。 Item:Q21699  |