Translations:Cannabis (drug)/59/en: Difference between revisions

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Message definition (Cannabis (drug))
THC is a weak partial agonist at [[CB1 receptor|CB<sub>1</sub> receptor]]s, while CBD is a [[CB1 receptor|CB<sub>1</sub> receptor]] antagonist.
The CB<sub>1</sub> receptor is found primarily in the brain as well as in some peripheral tissues, and the CB<sub>2</sub> receptor is found primarily in peripheral tissues, but is also expressed in [[neuroglia]]l cells. THC appears to alter mood and cognition through its agonist actions on the CB<sub>1</sub> receptors, which inhibit a [[secondary messenger system]] ([[adenylate cyclase]]) in a dose-dependent manner.

THC is a weak partial agonist at CB1 receptors, while CBD is a CB1 receptor antagonist. The CB1 receptor is found primarily in the brain as well as in some peripheral tissues, and the CB2 receptor is found primarily in peripheral tissues, but is also expressed in neuroglial cells. THC appears to alter mood and cognition through its agonist actions on the CB1 receptors, which inhibit a secondary messenger system (adenylate cyclase) in a dose-dependent manner.