Translations:Paricalcitol/1/en: Difference between revisions

Paricalcitol/1/en
Clinical data
Trade names	Zemplar
Other names	(1R,3S)-5-[2-[(1R,3aR,7aS)-1-[(2R,5S)-6-hydroxy-5,6-dimethyl-3E-hepten-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-cyclohexane-1,3-diol
AHFS/Drugs.com	Monograph
MedlinePlus	a682335
Pregnancy; category	AU: C; ;
Routes of; administration	Oral, Intravenous
ATC code	H05BX02 (WHO) ;
Legal status
Legal status	AU: S4 (Prescription only) ; CA: ℞-only ; UK: POM (Prescription only) ; US: ℞-only ;
Pharmacokinetic data
Bioavailability	72%
Protein binding	99.8%
Metabolism	Hepatic
Elimination half-life	14-20 hours
Excretion	Faeces (74%), urine (16%)
Identifiers
	IUPAC name (1R,3R,7E,17β)-17-[(1R,2E,4S)-5-hydroxy-1,4,5-trimethylhex-2-en-1-yl]-9,10-secoestra-5,7-diene-1,3-diol;
CAS Number	131918-61-1 ;
PubChem CID	5281104;
IUPHAR/BPS	2791;
DrugBank	DB00910 ;
ChemSpider	4444552 ;
UNII	6702D36OG5;
KEGG	D00930 ;
ChEBI	CHEBI:7931 ;
ChEMBL	ChEMBL1200622 ;
Chemical and physical data
Formula	C27H44O3
Molar mass	416.646 g·mol−1
	InChI InChI=1S/C27H44O3/c1-18(8-9-19(2)26(3,4)30)24-12-13-25-21(7-6-14-27(24,25)5)11-10-20-15-22(28)17-23(29)16-20/h8-11,18-19,22-25,28-30H,6-7,12-17H2,1-5H3/b9-8+,21-11+/t18-,19+,22-,23-,24-,25+,27-/m1/s1 ; Key:BPKAHTKRCLCHEA-UBFJEZKGSA-N ;
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Latest revision as of 23:14, 12 April 2024

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Message definition (Paricalcitol)

{{short description|Chemical compound}}
{{Drugbox
| Verifiedfields = changed
| Watchedfields = changed
| verifiedrevid = 445909355
| IUPAC_name = (1''R'',3''R'',7''E'',17β)-17-[(1''R'',2''E'',4''S'')-5-hydroxy-1,4,5-trimethylhex-2-en-1-yl]-9,10-secoestra-5,7-diene-1,3-diol
| image = Paricalcitol.svg
| width = 200px
| image2 = Paricalcitol3Dan.gif
| width2 = 200px

| tradename = Zemplar
| Drugs.com = {{drugs.com|monograph|paricalcitol}}
| MedlinePlus = a682335
| pregnancy_AU = C
| pregnancy_US = C
| pregnancy_category =
| legal_AU = S4
| legal_CA = Rx-only
| legal_UK = POM
| legal_US = Rx-only
| legal_status =
| routes_of_administration = Oral, Intravenous

| bioavailability = 72%
| protein_bound = 99.8%
| metabolism = [[Hepatic]]
| elimination_half-life = 14-20 hours
| excretion = Faeces (74%), urine (16%)

| CAS_number_Ref = {{cascite|correct|??}}
| CAS_number = 131918-61-1
| ATC_prefix = H05
| ATC_suffix = BX02
| ATC_supplemental =
| ChEBI_Ref = {{ebicite|changed|EBI}}
| ChEBI = 7931
| PubChem = 5281104
| IUPHAR_ligand = 2791
| DrugBank_Ref = {{drugbankcite|changed|drugbank}}
| DrugBank = DB00910
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 4444552
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = 6702D36OG5
| KEGG_Ref = {{keggcite|changed|kegg}}
| KEGG = D00930
| ChEMBL_Ref = {{ebicite|correct|EBI}}
| ChEMBL = 1200622

| chemical_formula =
| C=27 | H=44 | O=3
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C27H44O3/c1-18(8-9-19(2)26(3,4)30)24-12-13-25-21(7-6-14-27(24,25)5)11-10-20-15-22(28)17-23(29)16-20/h8-11,18-19,22-25,28-30H,6-7,12-17H2,1-5H3/b9-8+,21-11+/t18-,19+,22-,23-,24-,25+,27-/m1/s1
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = BPKAHTKRCLCHEA-UBFJEZKGSA-N
| synonyms = <small>(1''R'',3''S'')-5-[2-[(1''R'',3a''R'',7a''S'')-1-<nowiki>[</nowiki>(2''R'',5''S'')-6-hydroxy-5,6-dimethyl-3''E''-hepten-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1''H''-inden-4-ylidene]ethylidene]-cyclohexane-1,3-diol</small>
}}

Translations:Paricalcitol/1/en: Difference between revisions

Latest revision as of 23:14, 12 April 2024

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