Translations:Vitamin D5/3/en

1α-Hydroxyvitamin D₅ is a chemical derivative of vitamin D₅. The motive to study 1α-hydroxyvitamin D₅ as a potential pharmaceutical drug stemmed from the tendency of calcitriol, a natural metabolite produced in the kidney, to cause toxic hypercalcemia in patients when dosed at concentrations needed to interrupt prostate cancer cells' cycle and stimulate apoptosis. And while supplementation with dexamethasone decreases hypercalcemia, bypassing it with an equally effective tumor suppressant would reduce patient cost and stress. Thus, the therapeutic effects of 1α-Hydroxyvitamin D₅ as a potential antitumor agent without the side effects of calcitriol became a topic of study.