Translations:Vitamin D5/1/en: Difference between revisions

From Azupedia
Jump to navigation Jump to search
VisualWikitext
FuzzyBot (talk | contribs)
15,166 edits
Importing a new version from external source
 
(No difference)

Latest revision as of 21:36, 10 April 2024

Information about message (contribute)
This message has no documentation. If you know where or how this message is used, you can help other translators by adding documentation to this message.
Message definition (Vitamin D5)
{{short description|Fat soluble vitamin}}{{DISPLAYTITLE:Vitamin D<sub>5</sub>}}
{{chembox
| Verifiedfields = changed
| verifiedrevid = 470631138
| Name=Vitamin D<sub>5</sub>
| ImageFile=Vitamin D5 structure.svg
| ImageSize=
| IUPACName=(1''S'',3''Z'')-3-[(2''E'')-2-[(1''R'',3a''S'',7a''R'')-1-[(1''R'',4''S'')-4-ethyl-1,5-dimethylhexyl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1''H''-inden-4-ylidene]ethylidene]-4-methylene-1-cyclohexanol
| OtherNames= Sitocalciferol <br> (5''Z'',7''E'')-(3''S'')-9,10-secoporiferasta-5,7,10(19)-trien-3-ol
|Section1={{Chembox Identifiers
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 7826639
| ChEBI = 33279
| InChI = 1/C29H48O/c1-7-23(20(2)3)12-10-22(5)27-16-17-28-24(9-8-18-29(27,28)6)13-14-25-19-26(30)15-11-21(25)4/h13-14,20,22-23,26-28,30H,4,7-12,15-19H2,1-3,5-6H3/b24-13+,25-14-/t22-,23+,26+,27-,28+,29-/m1/s1
| InChIKey = RMDJVOZETBHEAR-GHTRHTQZBN
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C29H48O/c1-7-23(20(2)3)12-10-22(5)27-16-17-28-24(9-8-18-29(27,28)6)13-14-25-19-26(30)15-11-21(25)4/h13-14,20,22-23,26-28,30H,4,7-12,15-19H2,1-3,5-6H3/b24-13+,25-14-/t22-,23+,26+,27-,28+,29-/m1/s1
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = RMDJVOZETBHEAR-GHTRHTQZSA-N
| CASNo_Ref = {{cascite|correct|CAS}}
| CASNo=71761-06-3
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = 0W2I161LCL
| PubChem=9547700
| SMILES = O[C@@H]1CC(\C(=C)CC1)=C\C=C2/CCC[C@]3([C@H]2CC[C@@H]3[C@H](C)CC[C@H](CC)C(C)C)C
}}
|Section2={{Chembox Properties
| C=29 | H=48 | O=1
| Appearance=
| Density=
| MeltingPt=
| BoilingPt=
| Solubility=
  }}
|Section3={{Chembox Hazards
| MainHazards=
| FlashPt=
| AutoignitionPt =
  }}
}}
'''Vitamin D<sub>5</sub>''' ('''sitocalciferol''') is a form of [[vitamin D]].
== Research ==
[[structural analog|Analogs]] of [[calcitriol]], a form of vitamin D<sub>3</sub>, have been proposed for use as antitumor agents. Studies on vitamin D<sub>3</sub> have shown inhibition of cell proliferation in [[prostate cancer]], but high doses of vitamin D<sub>3</sub> result in [[Hypercalcaemia|hypercalcemia]]. The effects of vitamin D<sub>5</sub> on prostate cancer have also been studied, and unlike vitamin D<sub>3</sub>, vitamin D<sub>5</sub> does not cause [[Hypercalcaemia|hypercalcemia]] while inhibiting tumor cell proliferation. The most researched analogue of vitamin D<sub>5</sub> as an antitumor agent is 1α-hydroxyvitamin D<sub>5.</sub>
Vitamin D5
Names
IUPAC name
(1S,3Z)-3-[(2E)-2-[(1R,3aS,7aR)-1-[(1R,4S)-4-ethyl-1,5-dimethylhexyl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylene-1-cyclohexanol
Other names
Sitocalciferol
(5Z,7E)-(3S)-9,10-secoporiferasta-5,7,10(19)-trien-3-ol
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
UNII
Properties
C29H48O
Molar mass 412.702 g·mol−1

Vitamin D5 (sitocalciferol) is a form of vitamin D.

Research

Analogs of calcitriol, a form of vitamin D3, have been proposed for use as antitumor agents. Studies on vitamin D3 have shown inhibition of cell proliferation in prostate cancer, but high doses of vitamin D3 result in hypercalcemia. The effects of vitamin D5 on prostate cancer have also been studied, and unlike vitamin D3, vitamin D5 does not cause hypercalcemia while inhibiting tumor cell proliferation. The most researched analogue of vitamin D5 as an antitumor agent is 1α-hydroxyvitamin D5.

Retrieved from "https://wiki.tiffa.net/w/index.php?title=Translations:Vitamin_D5/1/en&oldid=136987"