Translations:Vitamin B12/28/en: Difference between revisions

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Message definition (Vitamin B12)
Serum [[haptocorrin]] binds 80-90% of circulating B<sub>12</sub>, rendering it unavailable for cellular delivery by [[Transcobalamin|transcobalamin II]]. This is conjectured to be a circulating storage function. Several serious, even life-threatening diseases cause elevated serum HC, measured as abnormally high serum vitamin B<sub>12</sub>, while at the same time potentially manifesting as a symptomatic vitamin deficiency because of insufficent vitamin bound to transcobalamin II which transfers the vitamin to cells.

Serum haptocorrin binds 80-90% of circulating B12, rendering it unavailable for cellular delivery by transcobalamin II. This is conjectured to be a circulating storage function. Several serious, even life-threatening diseases cause elevated serum HC, measured as abnormally high serum vitamin B12, while at the same time potentially manifesting as a symptomatic vitamin deficiency because of insufficent vitamin bound to transcobalamin II which transfers the vitamin to cells.