Fursultiamine: Difference between revisions

Created page with "<languages /> <translate> {{Short description|Chemical compound}} {{Drugbox | IUPAC_name = ''N''-[(4-Amino-2-methylpyrimidin-5-yl)methyl]-''N''-<nowiki>{</nowiki>(1''E'')-4-hydroxy-1-methyl-2-[(tetrahydrofuran-2-ylmethyl)disulfanyl]but-1-en-1-yl}formamide | image = Fursultiamine.png | alt = Skeletal formula of fursultiamine | width = 200 | image2 = Fursultiamine 3D ball.png | alt2 = Ball-and-stick model of the fursultiamine molecule | width2 = 200 <!--Clinical data--> |..."
 
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'''Fursultiamine''' ([[International Nonproprietary Name|INN]]; chemical name '''thiamine tetrahydrofurfuryl disulfide''' or '''TTFD'''; brand names '''Adventan''', '''Alinamin-F''', '''Benlipoid''', '''Bevitol Lipophil''', '''Judolor''', '''Lipothiamine''') is a medication and vitamin used to treat [[thiamine]] deficiency.  Chemically, it is a [[disulfide]] [[derivative (chemistry)|derivative]] of thiamine and is similar in structure to [[allithiamine]].
'''Fursultiamine''' ([[International Nonproprietary Name|INN]]; chemical name '''thiamine tetrahydrofurfuryl disulfide''' or '''TTFD'''; brand names '''Adventan''', '''Alinamin-F''', '''Benlipoid''', '''Bevitol Lipophil''', '''Judolor''', '''Lipothiamine''') is a medication and vitamin used to treat [[thiamine]] deficiency.  Chemically, it is a [[disulfide]] [[derivative (chemistry)|derivative]] of thiamine and is similar in structure to [[allithiamine]].


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It was synthesized in [[Japan]] in the 1960s from [[allithiamine]] for the purpose of developing forms of thiamine with improved [[lipophilicity]] for treating [[Thiamine#Deficiency|vitamin B<sub>1</sub> deficiency]] (i.e., [[beriberi]]), It was subsequently commercialized not only in Japan but also in [[Spain]], [[Austria]], [[Germany]], and the [[United States]].
It was synthesized in [[Japan]] in the 1960s from [[allithiamine]] for the purpose of developing forms of thiamine with improved [[lipophilicity]] for treating [[Thiamine#Deficiency|vitamin B<sub>1</sub> deficiency]] (i.e., [[beriberi]]), It was subsequently commercialized not only in Japan but also in [[Spain]], [[Austria]], [[Germany]], and the [[United States]].


== See also ==
== See also == <!--T:8-->
* [[Vitamin B1 analogue|Vitamin B<sub>1</sub> analogue]]
* [[Vitamin B1 analogue|Vitamin B<sub>1</sub> analogue]]


== Further reading ==
== Further reading == <!--T:9-->
* {{cite journal | vauthors = Lonsdale D | title = Thiamine tetrahydrofurfuryl disulfide: a little known therapeutic agent | journal = Medical Science Monitor | volume = 10 | issue = 9 | pages = RA199–203 | date = September 2004 | pmid = 15328496 | url = http://www.medscimonit.com/fulltxt.php?ICID=11763 }}
* {{cite journal | vauthors = Lonsdale D | title = Thiamine tetrahydrofurfuryl disulfide: a little known therapeutic agent | journal = Medical Science Monitor | volume = 10 | issue = 9 | pages = RA199–203 | date = September 2004 | pmid = 15328496 | url = http://www.medscimonit.com/fulltxt.php?ICID=11763 }}


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{{Vitamins}}
{{Vitamins}}


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{{二次利用|date=6 April 2023}}
{{二次利用|date=6 April 2023}}
[[Category:Formamides]]
[[Category:Formamides]]