Acefurtiamine/ja: Difference between revisions

Acefurtiamine/ja
Clinical data
ATC code	none;
Identifiers
	IUPAC name (3E)-4-{[(4-Amino-2-methylpyrimidin-5-yl)methyl](formyl)amino}-3-[(furan-2-ylcarbonyl)sulfanyl]pent-3-en-1-yl (acetyloxy)acetate;
CAS Number	10072-48-7 ;
PubChem CID	3037171;
ChemSpider	2300987 ;
UNII	6APJ3D1308;
ChEMBL	ChEMBL2104090 ;
Chemical and physical data
Formula	C21H24N4O7S
Molar mass	476.50 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C(OCC(=O)OCCC(\SC(=O)c1occc1)=C(/N(C=O)Cc2cnc(nc2N)C)C)C;
	InChI InChI=1S/C21H24N4O7S/c1-13(25(12-26)10-16-9-23-14(2)24-20(16)22)18(33-21(29)17-5-4-7-30-17)6-8-31-19(28)11-32-15(3)27/h4-5,7,9,12H,6,8,10-11H2,1-3H3,(H2,22,23,24)/b18-13+ ; Key:MYBUGVXNAHWTOL-QGOAFFKASA-N ;
	(what is this?) (verify)

Latest revision as of 08:26, 3 April 2024

アセフルチアミン（Acefurtiamine）（INN）は、チアミン誘導体クロメチアゾールのGABA作動活性に類似したビタミンB₁アナログである。十分な用量で鎮痛薬として機能する。

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 }}
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+'''アセフルチアミン'''（'''Acefurtiamine'''）（[[:en:International Nonproprietary Name|INN]]）は、[[thiamine/ja|チアミン]]誘導体[[clomethiazole/ja|クロメチアゾール]]の[[GABA/ja|GABA]]作動活性に類似した[[Vitamin B1 analogue/ja|ビタミンB<sub>1</sub>アナログ]]である。 十分な用量で[[analgesic/ja|鎮痛薬]]として機能する。
-'''Acefurtiamine''' ([[International Nonproprietary Name|INN]]) is a [[Vitamin B1 analogue|vitamin B<sub>1</sub> analog]] in a manner similar to the [[GABA]]ergic activity of the [[thiamine]] derivative [[clomethiazole]].  It functions as an [[analgesic]] agent at sufficient doses.
-</div>
-<div lang="en" dir="ltr" class="mw-content-ltr">
+== さらに読む ==
-== Further reading ==
 {{refbegin}}
 *{{cite book| veditors = Elks J, Ganellin CR |title=The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies|url=https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA2|date=1990|publisher=Springer|isbn=978-1-4757-2085-3|doi=10.1007/978-1-4757-2085-3|pages=2–}}
 {{refend}}
-</div>
-<div lang="en" dir="ltr" class="mw-content-ltr">
+{{Vitamins/ja}}
-{{Vitamins}}
-</div>
-<div lang="en" dir="ltr" class="mw-content-ltr">
-{{二次利用|date=6 February 2024}}
 [[Category:Analgesics]]
 [[Category:Acetate esters]]
@@ Line 66: / Line 58: @@
 [[Category:Thiamine]]
 [[Category:Formamides]]
-</div>

Clinical data

ATC code	none
Identifiers
IUPAC name (3E)-4-{[(4-Amino-2-methylpyrimidin-5-yl)methyl](formyl)amino}-3-[(furan-2-ylcarbonyl)sulfanyl]pent-3-en-1-yl (acetyloxy)acetate
CAS Number	10072-48-7^N
PubChem CID	3037171
ChemSpider	2300987^Y
UNII	6APJ3D1308
ChEMBL	ChEMBL2104090^N
Chemical and physical data
Formula	C₂₁H₂₄N₄O₇S
Molar mass	476.50 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES O=C(OCC(=O)OCCC(\SC(=O)c1occc1)=C(/N(C=O)Cc2cnc(nc2N)C)C)C
InChI InChI=1S/C21H24N4O7S/c1-13(25(12-26)10-16-9-23-14(2)24-20(16)22)18(33-21(29)17-5-4-7-30-17)6-8-31-19(28)11-32-15(3)27/h4-5,7,9,12H,6,8,10-11H2,1-3H3,(H2,22,23,24)/b18-13+^Y Key:MYBUGVXNAHWTOL-QGOAFFKASA-N^Y
^NY (what is this?) (verify)