Translations:Citric acid cycle/24/en: Difference between revisions

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Message definition (Citric acid cycle)
Some variability also exists at the previous step&nbsp;– the conversion of 2-oxoglutarate to succinyl-CoA. While most organisms utilize the ubiquitous NAD<sup>+</sup>-dependent 2-oxoglutarate dehydrogenase, some bacteria utilize a ferredoxin-dependent 2-oxoglutarate [[synthase]] ([http://www.enzyme-database.org/query.php?ec=1.2.7.3 EC 1.2.7.3]).
Other organisms, including obligately autotrophic and methanotrophic bacteria and archaea, bypass succinyl-CoA entirely, and convert 2-oxoglutarate to succinate via succinate semialdehyde, using [http://www.enzyme-database.org/query.php?ec=4.1.1.71 EC 4.1.1.71], 2-oxoglutarate decarboxylase, and [http://www.enzyme-database.org/query.php?ec=1.2.1.79 EC 1.2.1.79], succinate-semialdehyde dehydrogenase.

Some variability also exists at the previous step – the conversion of 2-oxoglutarate to succinyl-CoA. While most organisms utilize the ubiquitous NAD+-dependent 2-oxoglutarate dehydrogenase, some bacteria utilize a ferredoxin-dependent 2-oxoglutarate synthase (EC 1.2.7.3). Other organisms, including obligately autotrophic and methanotrophic bacteria and archaea, bypass succinyl-CoA entirely, and convert 2-oxoglutarate to succinate via succinate semialdehyde, using EC 4.1.1.71, 2-oxoglutarate decarboxylase, and EC 1.2.1.79, succinate-semialdehyde dehydrogenase.

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