Translations:Discovery and development of angiotensin receptor blockers/13/en: Difference between revisions

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Message definition (Discovery and development of angiotensin receptor blockers)
==Mechanism of action==
[[File:Renin ang pathway 2.jpg|right|thumb|350px|Fig 2. Renin angiotensin pathway]]
Blood pressure and fluid and electrolyte [[homeostasis]] is regulated by the [[renin–angiotensin–aldosterone system]].
[[Renin]], an enzyme released from the kidneys, converts the inactive plasma protein [[angiotensinogen]] into angiotensin I (Ang I).  Then Ang I is converted to Ang II with [[angiotensin converting enzyme]] (ACE), see figure 2. Ang II in plasma then binds to AT-receptors.

Mechanism of action

Fig 2. Renin angiotensin pathway

Blood pressure and fluid and electrolyte homeostasis is regulated by the renin–angiotensin–aldosterone system. Renin, an enzyme released from the kidneys, converts the inactive plasma protein angiotensinogen into angiotensin I (Ang I). Then Ang I is converted to Ang II with angiotensin converting enzyme (ACE), see figure 2. Ang II in plasma then binds to AT-receptors.

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