Translations:Insulin (medication)/17/en: Difference between revisions

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Message definition (Insulin (medication))
== Principles ==
[[File:Suckale08 fig3 glucose insulin day.png|thumb|The idealised diagram shows the fluctuation of [[blood sugar]] (red) and the sugar-lowering hormone insulin (blue) in humans during the course of a day containing three meals. In addition, the effect of a [[sucrose|sugar]]-rich versus a [[starch]]-rich meal is highlighted.]]
{|class="collapsible collapsed" align="right" width="400" border="1" bgcolor="powderblue"|
! bgcolor="#BCD2EE" colspan="8" |Amino Acid Sequence of Insulin Preparations
|-
! colspan="8" bgcolor="azure"| Amino Acid Substitutions
|-
! colspan=1 bgcolor="azure" |
 
! colspan=3 bgcolor="azure" |
  A-Chain Position  
! colspan=4 bgcolor="azure" |
B-Chain Position
|-
! width="120" bgcolor="azure" | Source<br />Species
! width="70" bgcolor="azure" | A-8
! width="70" bgcolor="azure" | A-10
! width="70" bgcolor="azure" | A-21
! width="70" bgcolor="azure" | B-28
! width="70" bgcolor="azure" | B-29
! width="70" bgcolor="azure" | B-30
! width="70" bgcolor="azure" | B-31<br />B-32
|-
! bgcolor="ivory" | Bovine
! bgcolor="ivory" | Ala
! bgcolor="ivory" | Val
! bgcolor="ivory" | Asn
! bgcolor="ivory" | Pro
! bgcolor="ivory" | Lys
! bgcolor="ivory" | Ala
! bgcolor="ivory" | N/A
|-
! bgcolor="ivory" | Porcine
! bgcolor="ivory" | Thr
! bgcolor="ivory" | Ile
! bgcolor="ivory" | Asn
! bgcolor="ivory" | Pro
! bgcolor="ivory" | Lys
! bgcolor="ivory" | Ala
! bgcolor="ivory" | N/A
|-
! bgcolor="ivory" | Human
! bgcolor="ivory" | Thr
! bgcolor="ivory" | Ile
! bgcolor="ivory" | Asn
! bgcolor="ivory" | Pro
! bgcolor="ivory" | Lys
! bgcolor="ivory" | Thr
! bgcolor="ivory" | N/A
|-
! bgcolor="powderblue" | [[Aspart]] (Novolog)
! bgcolor="ivory" | Thr
! bgcolor="ivory" | Ile
! bgcolor="ivory" | Asn
! bgcolor="powderblue" | Asp
! bgcolor="ivory" | Lys
! bgcolor="ivory" | Thr
! bgcolor="ivory" | N/A
|-
! bgcolor="powderblue" | [[Lispro]] (Humalog)
! bgcolor="ivory" | Thr
! bgcolor="ivory" | Ile
! bgcolor="ivory" | Asn
! bgcolor="powderblue" | Lys
! bgcolor="powderblue" | Pro
! bgcolor="ivory" | Thr
! bgcolor="ivory" | N/A
|-
! bgcolor="powderblue" | [[Glulisine]] (Apidra)
! bgcolor="ivory" | Thr
! bgcolor="ivory" | Ile
! bgcolor="ivory" | Asn
! bgcolor="ivory" | Pro
! bgcolor="powderblue" | Glu
! bgcolor="ivory" | Thr
! bgcolor="ivory" | N/A
|- width="400" border="1"
! bgcolor="powderblue" | [[Glargine]] (Lantus)
! bgcolor="ivory" | Thr
! bgcolor="ivory" | Ilc
! bgcolor="powderblue" | Gly
! bgcolor="ivory" | Pro
! bgcolor="ivory" | Lys
! bgcolor="ivory" | Thr
! bgcolor="powderblue" | Arg
|-
! bgcolor="powderblue" | [[Detemir]](Levemir)
! bgcolor="ivory" | Thr
! bgcolor="ivory" | Ile
! bgcolor="ivory" | Asn
! bgcolor="ivory" | Pro
! bgcolor="ivory" | Lys
! bgcolor="powderblue" | N/A
! bgcolor="powderblue" | [[Myristic acid]]
|-
! bgcolor="powderblue" | [[Insulin degludec|Degludec]](Tresiba)
! bgcolor="ivory" | Thr
! bgcolor="ivory" | Ile
! bgcolor="ivory" | Asn
! bgcolor="ivory" | Pro
! bgcolor="ivory" | Lys
! bgcolor="powderblue" | N/A
! bgcolor="powderblue" | [[Hexadecanedioic acid]]
|-
| bgcolor="azure" colspan=8|
{{center|1='''Ala=Alanine Val=Valine Asn=Asparagine Pro=Proline Lys=Lysine Thr=Threonine Ile=Isoleucine Glu=Glutamine Gly=Glycine'''}}
|}

Principles

The idealised diagram shows the fluctuation of blood sugar (red) and the sugar-lowering hormone insulin (blue) in humans during the course of a day containing three meals. In addition, the effect of a sugar-rich versus a starch-rich meal is highlighted.
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