Translations:Insulin/14/en: Difference between revisions

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Latest revision as of 16:33, 18 March 2024

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Message definition (Insulin)
[[MafA]] is degraded by [[proteasomes]] upon low blood [[glucose]] levels. Increased levels of [[glucose]] make an unknown protein [[glycosylated]]. This protein works as a transcription factor for [[MafA]] in an unknown manner and [[MafA]] is transported out of the cell. [[MafA]] is then translocated back into the nucleus where it binds the C1 element of the insulin promoter.

MafA is degraded by proteasomes upon low blood glucose levels. Increased levels of glucose make an unknown protein glycosylated. This protein works as a transcription factor for MafA in an unknown manner and MafA is transported out of the cell. MafA is then translocated back into the nucleus where it binds the C1 element of the insulin promoter.