Translations:Sulfonylurea/23/en: Difference between revisions

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Message definition (Sulfonylurea)
===Classification===
Sulfonylureas are divided into 3 classes on basis of therapeutic efficiency of their antidiabetic action:
* First-generation drugs:
They include [[acetohexamide]], [[carbutamide]], [[chlorpropamide]], [[glycyclamide]] (tolcyclamide), [[metahexamide]], [[tolazamide]] and [[tolbutamide]].
* Second-generation drugs:
They include [[glibenclamide]] (glyburide), [[glibornuride]], [[gliclazide]], [[glipizide]], [[gliquidone]], [[glisoxepide]] and [[glyclopyramide]].
* Third-generation drugs:
They include [[glimepiride]], although it is sometimes considered a second-generation drug.
===Mechanism of action===
[[File:Glucose Insulin Release Pancreas.svg|thumb|Diagram of glucose reduction and insulin release in the pancreas]]

Classification

Sulfonylureas are divided into 3 classes on basis of therapeutic efficiency of their antidiabetic action:

  • First-generation drugs:

They include acetohexamide, carbutamide, chlorpropamide, glycyclamide (tolcyclamide), metahexamide, tolazamide and tolbutamide.

  • Second-generation drugs:

They include glibenclamide (glyburide), glibornuride, gliclazide, glipizide, gliquidone, glisoxepide and glyclopyramide.

  • Third-generation drugs:

They include glimepiride, although it is sometimes considered a second-generation drug.

Mechanism of action

Diagram of glucose reduction and insulin release in the pancreas
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