Translations:Sulfonylurea/23/en
Classification
Sulfonylureas are divided into 3 classes on basis of therapeutic efficiency of their antidiabetic action:
- First-generation drugs:
They include acetohexamide, carbutamide, chlorpropamide, glycyclamide (tolcyclamide), metahexamide, tolazamide and tolbutamide.
- Second-generation drugs:
They include glibenclamide (glyburide), glibornuride, gliclazide, glipizide, gliquidone, glisoxepide and glyclopyramide.
- Third-generation drugs:
They include glimepiride, although it is sometimes considered a second-generation drug.
Mechanism of action
