Latest revision as of 08:46, 12 March 2024
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Message definition (Metformin ) Metformin also interacts with [[anticholinergic]] medications, due to their effect on gastric motility. Anticholinergic drugs reduce gastric motility, prolonging the time drugs spend in the [[gastrointestinal tract]]. This impairment may lead to more metformin being absorbed than without the presence of an anticholinergic drug, thereby increasing the concentration of metformin in the plasma and increasing the risk for adverse effects.
メトホルミンはまた、胃運動への影響により抗コリン薬 とも相互作用する。抗コリン薬は胃の運動性を低下させ、薬が消化管 に留まる時間を延長させる。この障害により、抗コリン薬が存在しない場合よりもメトホルミンが多く吸収され、血漿中のメトホルミン濃度が上昇し、副作用のリスクが高まる可能性がある。