Translations:Insulin resistance/23/en: Difference between revisions

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Latest revision as of 09:44, 10 March 2024

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Message definition (Insulin resistance)
Insulin resistance in [[adipose tissue|fat cells]] results in reduced uptake of circulating lipids and increased [[hydrolysis]] of stored [[triglyceride]]s. This leads to elevated free [[fatty acid]]s in the [[blood plasma]] and can further worsen insulin resistance. Since insulin is the primary hormonal signal for energy storage into [[fat cells]], which tend to retain their sensitivity in the face of hepatic and skeletal muscle resistance, insulin resistance stimulates the formation of new fatty tissue and accelerates weight gain.

Insulin resistance in fat cells results in reduced uptake of circulating lipids and increased hydrolysis of stored triglycerides. This leads to elevated free fatty acids in the blood plasma and can further worsen insulin resistance. Since insulin is the primary hormonal signal for energy storage into fat cells, which tend to retain their sensitivity in the face of hepatic and skeletal muscle resistance, insulin resistance stimulates the formation of new fatty tissue and accelerates weight gain.