Translations:GLP-1 receptor agonist/21/en: Difference between revisions

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Message definition (GLP-1 receptor agonist)
==Combination and multiple target drugs==
{{see also|GLP1 poly-agonist peptides}}
Some GLP-1 agonists, such as [[tirzepatide]], are also agonists of the [[GIP receptor]] and/or [[glucagon receptor]]. These additional targets are hoped to improve the amount of weight loss caused by the drugs. Combination with glucagon agonism is likely to make the drugs more efficacious for weight loss, at the expense of additional risk and a lower [[therapeutic index]].

Combination and multiple target drugs

Some GLP-1 agonists, such as tirzepatide, are also agonists of the GIP receptor and/or glucagon receptor. These additional targets are hoped to improve the amount of weight loss caused by the drugs. Combination with glucagon agonism is likely to make the drugs more efficacious for weight loss, at the expense of additional risk and a lower therapeutic index.