Translations:Vitamin D/98/en: Difference between revisions

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Message definition (Vitamin D)
Whether synthesized in the skin or ingested, vitamin D is [[hydroxylated]] in the [[liver]] at position 25 (upper right of the molecule) to form 25-hydroxycholecalciferol (calcifediol or 25(OH)D). This reaction is catalyzed by the [[Microsome|microsomal]] enzyme [[vitamin D 25-hydroxylase]], the product of the ''CYP2R1'' human gene, and expressed by [[hepatocytes]]. Once made, the product is released into the [[blood plasma|plasma]], where it is bound to an α-globulin carrier protein named the [[vitamin D-binding protein]].

Whether synthesized in the skin or ingested, vitamin D is hydroxylated in the liver at position 25 (upper right of the molecule) to form 25-hydroxycholecalciferol (calcifediol or 25(OH)D). This reaction is catalyzed by the microsomal enzyme vitamin D 25-hydroxylase, the product of the CYP2R1 human gene, and expressed by hepatocytes. Once made, the product is released into the plasma, where it is bound to an α-globulin carrier protein named the vitamin D-binding protein.

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