Translations:Xanthine oxidase inhibitor/7/en
| 一般名 | 先発名 | 日本 | 創薬/開発 | 備考 |
|---|---|---|---|---|
| allopurinol/ja | ザイロリック(Zyloric) | 販売 | GSK plc | |
| febuxostat/ja | フェブリク(Febric) (PI) (IF) | 販売 | 帝人ファーマ | |
| topiroxostat/ja | ウリアデック(Uriadec) | 販売 | 三和化学研究所 |
A xanthine oxidase inhibitor is any substance that inhibits the activity of xanthine oxidase, an enzyme involved in purine metabolism. In humans, inhibition of xanthine oxidase reduces the production of uric acid, and several medications that inhibit xanthine oxidase are indicated for treatment of hyperuricemia and related medical conditions including gout. Xanthine oxidase inhibitors are being investigated for management of reperfusion injury.