Translations:Discovery and development of angiotensin receptor blockers/10/en

Distribution in the body

AT₁ receptors are mainly found in the heart, adrenal glands, brain, liver and kidneys. Their main role is to regulate blood pressure as well as fluid and electrolyte balance.
AT₂ receptors are highly expressed in the developing fetus but they decline rapidly after birth. In the adult, AT₂ receptors are present only at low levels and are mostly found in the heart, adrenal glands, uterus, ovaries, kidneys and brain.