...ther substances. In this process, bonds between atoms may be broken and/or new bonds formed.
...mpounds, distinguished by how the constituent atoms are bonded together. [[Molecular compound]]s are held together by [[covalent bond]]s; [[ionic compound]]s ar
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19 KB (2,660 words) - 08:18, 5 January 2023
{{Short description|Process of bringing a new pharmaceutical drug to the market}}
...ns, and may include the step of obtaining [[regulatory approval]] with a [[new drug application]] to market the drug.<ref name=":0">{{cite book| vauthors
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26 KB (3,425 words) - 08:08, 4 January 2023
| location = [[Wikipedia:Rahway, New Jersey|Rahway, New Jersey]], {{Country|アメリカ}}
'''Merck & Co., Inc.'''（'''Merck & Co., Inc.'''）は、アメリカの[[:en:Rahway, New Jersey|ニュージャージー州ラーウェイ]]に本社を置く[[:en:Multinational corporation|多国籍]][[pharmac
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48 KB (1,749 words) - 22:11, 14 March 2024
{{short description|Process by which new candidate medications are discovered}}
...ology]] and [[pharmacology]], '''drug discovery''' is the process by which new candidate [[pharmaceutical drug|medications]] are discovered.<ref name="fda
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55 KB (7,244 words) - 08:05, 4 January 2023
...|pharmacology]], [[drug discovery|drug discovery]] is the process by which new drugs are discovered.
...research and development cost of each [[new molecular entity|new molecular entity]] (NME) was approximately US$1.8 billion. Drug discovery is done by pharmac
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52 KB (6,923 words) - 17:09, 5 November 2023
...|pharmacology]], [[drug discovery|drug discovery]] is the process by which new drugs are discovered.
...research and development cost of each [[new molecular entity|new molecular entity]] (NME) was approximately US$1.8 billion. Drug discovery is done by pharmac
...
54 KB (7,245 words) - 17:08, 5 November 2023
...tle = Inhibitory monoclonal antibodies to human cytochrome P450 enzymes: a new avenue for drug discovery | journal = Trends in Pharmacological Sciences |
...t. This capability has become an investigative tool in [[biochemistry]], [[molecular biology]], and [[medicine]]. Monoclonal antibodies are being used on a clin
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44 KB (5,708 words) - 17:44, 3 January 2023
...物探索は依然として時間がかかり、「高価で、困難で、非効率的なプロセス」であり、新しい治療法の発見率は低い。2010年、[[new molecular entity/ja|新規分子化合物]]（NME）1つあたりの研究開発費は約18億米ドルだった。薬物の創製は製薬会社によって行われ、時には大学の研究支援を受けることも
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58 KB (1,845 words) - 17:09, 5 November 2023
...ignalling and efforts to exploit these observations for the development of new drugs. The blood pressure raising and vasoconstrictive effects of adrenal e
...in depression and other psychiatric indications. It received approval as a New and Nonofficial Remedy from the [[American Medical Association]] for these
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60 KB (8,551 words) - 22:13, 8 January 2023
| headquarters = White Oak Campus<br />10903 [[Maryland Route 650|New Hampshire Avenue]]<br />[[Silver Spring, Maryland]] 20993
..., Maryland]]. In 2001, the [[General Services Administration]] (GSA) began new construction on the campus to consolidate the FDA's 25 existing operations
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60 KB (8,770 words) - 08:38, 9 January 2023
...rocess can be used to remove, or "[[Gene knockout|knock out]]", genes. The new DNA can be inserted randomly, or [[Gene targeting|targeted]] to a specific
...ngineering is considered to be genetically modified (GM) and the resulting entity is a [[genetically modified organism]] (GMO). The first GMO was a [[Genetic
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133 KB (18,146 words) - 07:51, 4 January 2023
...as been created much more recently, in relation to the new developments in molecular biology over the last fifty years, more particularly in epigenetics, which
Primal prevention is health promotion ''par excellence''. New knowledge in molecular biology, in particular [[epigenetics]], points to how much affective as wel
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65 KB (9,447 words) - 19:57, 11 January 2023
...of some forms of [[diabetes mellitus type 1]], even though the particular molecular pathways by which it works are not yet understood. It is also common to kno
...hysiologic process]]" rather than ''disease'' implying "a specific disease entity as defined by diagnostic criteria being already met". This is hard to quant
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42 KB (6,184 words) - 21:37, 28 February 2024
...of some forms of [[diabetes mellitus type 1]], even though the particular molecular pathways by which it works are not yet understood. It is also common to kno
...hysiologic process]]" rather than ''disease'' implying "a specific disease entity as defined by diagnostic criteria being already met". This is hard to quant
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43 KB (6,288 words) - 21:36, 28 February 2024
...Biology | publisher = Pearson | edition = 11th | date = 2017 | location = New York | pages = 2–26 | isbn = 978-0134093413}}</ref><ref name = "hillis2020"
...f research methods in biology|tool]]s that they use.<ref>{{Cite book|title=Molecular Biology, Principles of Genome Function|last=Craig|first=Nancy|year=2014|isb
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274 KB (38,277 words) - 22:26, 3 January 2023