File:Metformin synthesis.svg
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Summary
| Description |
English: Chemical synthesis of metformin, as reported by Seymour L. Shapiro et al. in 1959. Dimethylamine (1) and 2-cyanoguanidine (2) react at 120–140°C to form metformin (3). Created using ACD/ChemSketch 10.0, Inkscape and vim. |
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| Date | ||||
| Source | Own work, after Bretnall, Alison E.; Graham S. Clarke (1998) Brittain, Harry G. , ed. Analytical Profiles of Drug Substances & Excipients (Profiles of Drug Substances, Excipients, and Related Methodology), Boston: Academic Press, pp. 250 ISBN 0-12-260825-9 | |||
| Author | Fvasconcellos | |||
| Permission (Reusing this file) |
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File history
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 05:40, 8 December 2009 | | 525 × 168 (12 KB) | wikimediacommons>Fvasconcellos | {{validSVG}} == {{int:filedesc}} == {{Information |Description= {{en|1={{w|Chemical synthesis}} of {{w|metformin}}, as reported by Seymour L. Shapiro ''et al.'' in 1959.<br>{{w|Dimethylamine}} '''(1)''' and {{w|2-cyanoguanidine}} '''(2)''' react at 120� |
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