Translations:Discovery and development of angiotensin receptor blockers/11/en

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Functions

Most of the known actions of Ang II are mediated through the AT1 receptors, for example vasoconstriction, aldosterone release, renal sodium reabsorption and vasopressin secretion. The AT2 receptor also takes part in regulation of blood pressure and renal function but mediates antagonistic effects compared to the AT1 receptor.